No need to use the Oracle VM to run ISE on Win10, just follow these steps:

1) Install ISE14.7 for Windows (Embedded Edition) on your Win10 computer
2) Go to C:\Xilinx\14.7\ISE_DS\ISE\lib\nt64 (assuming 64-bit Win10) and rename libPortability.dll to libPortability_orig.dll
3) Make a copy of libPortabilityNOSH.dll and rename it libPortability.dll
4) Go to C:\Xilinx\14.7\ISE_DS\EDK\lib\nt64 and rename libPortability.dll to libPortability_orig.dll
5) Copy libPortability.dll from C:\Xilinx\14.7\ISE_DS\ISE\lib\nt64 to C:\Xilinx\14.7\ISE_DS\EDK\lib\nt64
6) Run ISE and install your license file etc. You should now have a working version of ISE on your Win10 computer. Magnus